Texas Instruments has a great Online tool, TI Webench to design Voltage Regulators and more. It makes it seamlessly easy to customize a DC Regulator for example. It's huge, cool, a time saver.
DC Regulators, every circuit needs some power. Maxim did have a Webinar, showing of differences, in topology and their new power module. It's short, and informative. The module is also really small. Maxim Wide Input DC-DC Voltage Regulator Design Made Easy
Changing layers on a larger board, can take a lots of mouse clicks. If you know what layers you need, keyboard short-cuts are great. Created a bunch of scripts, that lets you easy add and subtract layers, what are current active. Without walking the menu. Helps reduce the eyestrain too.
Between routing and placement, lots of time we'd need to change the grid. Clicking on the menu, and typing in the numbers is time consuming. Created some scripts, in combination with an alias, is pretty slick and fast to change the grids.